DMG should not be confused with TMG (trimethylglycine or betaine). DMG is also known as N, N-dimethylglycine, (dimethylamino)acetic acid and N-methylsarcosine.ĭMG is a solid, water-soluble substance. DMG is neither a vitamin nor an essential nutrient. None of those claims, however, was ever substantiated. At present, DMG supplements are available that do contain dimethylglycine.ĭMG-containing calcium pangamate was popular with Russian athletes and cosmonauts because it was reputed to enhance oxygenation at the cellular level, reduce fatigue and enhance physical stamina. Some of these products contained, instead of DMG, a substance called diisopropylammonium dichloroacetate.
However, several products entered the supplement marketplace called pangamic acid or calcium pangamate, and these did not contain DMG. Calcium pangamate was intended as a delivery form of DMG.
Calcium pangamate was originally a mixture of calcium gluconate and DMG. DMG appeared as a supplement in the 1960s under the names vitamin B15, pangamic acid and calcium pangamate. There has been much confusion surrounding the history of DMG as a nutritional supplement. DMG is produced in cells as an intermediate in the metabolism of choline to glycine. Dimethylglycine or DMG is a non-protein amino acid found naturally in animal and plant cells.
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